Research Paper
SNHG16 upregulation-induced positive feedback loop with YAP1/TEAD1 complex in Colorectal Cancer cell lines facilitates liver metastasis of colorectal cancer by modulating CTCs epithelial-mesenchymal transition
Zhenxian Xiang, Guoquan Huang, Haitao Wu, Qiuming He, Chaogang Yang, Rongzhang Dou, Qing Liu, Jialing Song, Yan Fang, Shuyi Wang, Bin Xiong
Int. J. Biol. Sci. 2022; 18(14): 5291-5308. doi:10.7150/ijbs.73438
[Abstract] [Full text] [PDF]

Review
Mitochondrial quality control in diabetic cardiomyopathy: from molecular mechanisms to therapeutic strategies
Chen Cai, Feng Wu, Jing He, Yaoyuan Zhang, Nengxian Shi, Xiaojie Peng, Qing Ou, Ziying Li, Xiaoqing Jiang, Jiankai Zhong, Ying Tan
Int. J. Biol. Sci. 2022; 18(14): 5276-5290. doi:10.7150/ijbs.75402
[Abstract] [Full text] [PDF]

Research Paper
Covalent Inhibition of Pyruvate Kinase M2 Reprograms Metabolic and Inflammatory Pathways in Hepatic Macrophages against Non-alcoholic Fatty Liver Disease
Ni Fan, Xiuying Zhang, Wei Zhao, Jia Zhao, Dan Luo, Yilu Sun, Ding Li, Chenliang Zhao, Yu Wang, Hongjie Zhang, Jianhui Rong
Int. J. Biol. Sci. 2022; 18(14): 5260-5275. doi:10.7150/ijbs.73890
[Abstract] [Full text] [PDF]

Research Paper
SPC25 promotes proliferation and stemness of hepatocellular carcinoma cells via the DNA-PK/AKT/Notch1 signaling pathway
Jieying Yang, Yue Huang, Mengjia Song, Qiuzhong Pan, Jingjing Zhao, Junyi He, Dijun Ouyang, Chaopin Yang, Yulong Han, Yan Tang, Qijing Wang, Jia He, Yongqiang Li, Hao Chen, Desheng Weng, Tong Xiang, JianChuan Xia
Int. J. Biol. Sci. 2022; 18(14): 5241-5259. doi:10.7150/ijbs.71694
[Abstract] [Full text] [PDF]

Research Paper
Inhibition of APOE potentiates immune checkpoint therapy for cancer
Bingqing Hui, Chen Lu, Haiyang Li, Xiaopei Hao, Hanyuan Liu, Danping Zhuo, Qian Wang, Zhouxiao Li, Li Liu, Xuehao Wang, Yanhong Gu, Weiwei Tang
Int. J. Biol. Sci. 2022; 18(14): 5230-5240. doi:10.7150/ijbs.70117
[Abstract] [Full text] [PDF]

Research Paper
MG53 inhibits cellular proliferation and tumor progression in colorectal carcinoma
Pranav Gupta, Haichang Li, Guan-Nan Zhang, Anna Maria Barbuti, Yuqi Yang, Pei-hui Lin, Chuanxi Cai, Tao Tan, Jianjie Ma, Zhe-Sheng Chen
Int. J. Biol. Sci. 2022; 18(14): 5221-5229. doi:10.7150/ijbs.67869
[Abstract] [Full text] [PDF]

Research Paper
Nitroxoline suppresses metastasis in bladder cancer via EGR1/circNDRG1/miR-520h/smad7/EMT signaling pathway
Liangliang Ren, Minxiao Jiang, Dingwei Xue, Huan Wang, Zeyi Lu, Lifeng Ding, Haiyun Xie, Ruyue Wang, Wenqin Luo, Li Xu, Mingchao Wang, Shicheng Yu, Sheng Cheng, Liqun Xia, Haifeng Yu, Peng Huang, Naijin Xu, Gonghui Li
Int. J. Biol. Sci. 2022; 18(13): 5207-5220. doi:10.7150/ijbs.69373
[Abstract] [Full text] [PDF]

Review
The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways
Haoming Luo, Mingxing Li, Fang Wang, Yifei Yang, Qin Wang, Yueshui Zhao, Fukuan Du, Yu Chen, Jing Shen, Qianyun Zhao, Jiuping Zeng, Shengpeng Wang, Meijuan Chen, Xiaobing Li, Wanping Li, Yuhong Sun, Li Gu, Qinglian Wen, Zhangang Xiao, Xu Wu
Int. J. Biol. Sci. 2022; 18(13): 5185-5206. doi:10.7150/ijbs.72600
[Abstract] [Full text] [PDF]

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