Research Paper
Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway
Yalan Dong, Heng Fan, Zhe Zhang, Feng Jiang, Mingyue Li, Haifeng Zhou, Weina Guo, Zili Zhang, Zhenyu Kang, Yang Gui, Zhexing Shou, Junyi Li, Rui Zhu, Yu Fu, Alexey Sarapultsev, Huafang Wang, Shanshan Luo, Ge Zhang, Desheng Hu
Int. J. Biol. Sci. 2022; 18(4): 1381-1397. doi:10.7150/ijbs.65476
[Abstract] [Full text] [PDF]

Research Paper
Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop
Chong Zhou, Xi He, Chang Tong, Honghui Li, Caifeng Xie, Yudong Wu, Lieliang Wang, Xiaohua Yan, Daya Luo, Yunpeng Tang, Zhongman Cheng, Xiangyang Xiong
Int. J. Biol. Sci. 2022; 18(4): 1363-1380. doi:10.7150/ijbs.65227
[Abstract] [Full text] [PDF]

Research Paper
LncRNA-COX2 inhibits Fibroblast Activation and Epidural Fibrosis by Targeting EGR1
Lei Yang, Shengnai Zheng, Dawei Ge, Mingjie Xia, Haijun Li, Jian Tang
Int. J. Biol. Sci. 2022; 18(4): 1347-1362. doi:10.7150/ijbs.67974
[Abstract] [Full text] [PDF]

Research Paper
Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury
Zhanyang Qian, Hongtao Chen, Mingjie Xia, Jie Chang, Xinyu Li, Suhui Ye, Shunjie Wu, Shuai Jiang, Junping Bao, Binyu Wang, Renyi Kong, Sheng Zhang, Shengnai Zheng, Xiaojian Cao, Xin Hong
Int. J. Biol. Sci. 2022; 18(4): 1328-1346. doi:10.7150/ijbs.68974
[Abstract] [Full text] [PDF]

Review
Advances in Multi-Omics Study of Prognostic Biomarkers of Diffuse Large B-Cell Lymphoma
Xiao-jie Liang, Xin-yu Song, Jia-lin Wu, Dan Liu, Bing-yu Lin, Hong-sheng Zhou, Liang Wang
Int. J. Biol. Sci. 2022; 18(4): 1313-1327. doi:10.7150/ijbs.67892
[Abstract] [Full text] [PDF]

Review
Role of Slit/Robo Signaling pathway in Bone Metabolism
Lingyu Jiang, Jianxun Sun, Dingming Huang
Int. J. Biol. Sci. 2022; 18(3): 1303-1312. doi:10.7150/ijbs.66931
[Abstract] [Full text] [PDF]

Research Paper
VRK2 activates TNFα/NF-κB signaling by phosphorylating IKKβ in pancreatic cancer
Jionghuang Chen, Kexiong Qiao, Chaolei Zhang, Xinyang Zhou, Qian Du, Yuezhen Deng, Liping Cao
Int. J. Biol. Sci. 2022; 18(3): 1288-1302. doi:10.7150/ijbs.66313
[Abstract] [Full text] [PDF]

Research Paper
CXCR4-dependent macrophage-to-fibroblast signaling contributes to cardiac diastolic dysfunction in heart failure with preserved ejection fraction
Ning Zhang, Qunchao Ma, Yayu You, Xiangyang Xia, Cuiping Xie, Yuxue Huang, Zhuo Wang, Feiming Ye, Zhaosheng Yu, Xiaojie Xie
Int. J. Biol. Sci. 2022; 18(3): 1271-1287. doi:10.7150/ijbs.65802
[Abstract] [Full text] [PDF]

Research Paper
Integrin-β4 regulates the dynamic changes of phenotypic characteristics in association with epithelial-mesenchymal transition (EMT) and RhoA activity in airway epithelial cells during injury and repair
Mei-Ling Tan, Wen-Jie Huang, Yue Wang, Lei Liu, Yan Pan, Jing-Jing Li, Jiang Zhang, Mingxing Ouyang, Xiang-Ping Qu, Hui-Jun Liu, Chi Liu, Dan Zeng, Xiao-Qun Qin, Linhong Deng, Yang Xiang
Int. J. Biol. Sci. 2022; 18(3): 1254-1270. doi:10.7150/ijbs.65174
[Abstract] [Full text] [PDF]

Research Paper
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation
Fangfei Li, Xiaoqiu Wu, Xuekun Fu, Jin Liu, Wangze Song, Gary Guishan Xiao, Aiping Lu, Ge Zhang
Int. J. Biol. Sci. 2022; 18(3): 1238-1253. doi:10.7150/ijbs.58784
[Abstract] [Full text] [PDF]

Research Paper
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression
Kai Chen, Qi Wang, Xinxin Liu, Feng Wang, Yinmo Yang, Xiaodong Tian
Int. J. Biol. Sci. 2022; 18(3): 1220-1237. doi:10.7150/ijbs.67675
[Abstract] [Full text] [PDF]

Review
DNA Replication Licensing Factors: Novel Targets for Cancer Therapy via Inhibiting the Stemness of Cancer Cells
Shaoran Song, Yaochun Wang, Peijun Liu
Int. J. Biol. Sci. 2022; 18(3): 1211-1219. doi:10.7150/ijbs.67529
[Abstract] [Full text] [PDF]

Research Paper
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer
Zhiyuan Dou, Chunping Qiu, Xun Zhang, Shu Yao, Chen Zhao, Zixiang Wang, Ran Chu, Jingying Chen, Zhongshao Chen, Rongrong Li, Kun Wang, Penglin Liu, Chang Liu, Kun Song, Beihua Kong
Int. J. Biol. Sci. 2022; 18(3): 1188-1210. doi:10.7150/ijbs.65589
[Abstract] [Full text] [PDF]

Research Paper
CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis
Haotian Wei, Li Chen, Qing Li, Xinjun Liang, Kun Wang, Ying Zhang, Yueqiang Li, Yanyan Liu, Gang Xu
Int. J. Biol. Sci. 2022; 18(3): 1171-1187. doi:10.7150/ijbs.66781
[Abstract] [Full text] [PDF]

Review
Insight of Autophagy in Spontaneous Miscarriage
Xue-Yun Qin, Hui-Hui Shen, Wen-Jie Zhou, Jie Mei, Han Lu, Xiao-Fang Tan, Rui Zhu, Wen-Hui Zhou, Da-Jin Li, Tao Zhang, Jiang-Feng Ye, Ming-Qing Li
Int. J. Biol. Sci. 2022; 18(3): 1150-1170. doi:10.7150/ijbs.68335
[Abstract] [Full text] [PDF]

Research Paper
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma
Hongjuan Xu, Xuejun Yan, Hecheng Zhu, Yuanbo Kang, Weiren Luo, Jin Zhao, Kefan Zhou, Xiwu Liu, Li Ye, Quanwei Zhou, Shasha Li, Ming Zhao, Lei Wang, Bin Zhu, Weidong Liu, Jianxiong Li, Xingjun Jiang, Caiping Ren
Int. J. Biol. Sci. 2022; 18(3): 1134-1149. doi:10.7150/ijbs.68091
[Abstract] [Full text] [PDF]

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