International Journal of Biological Sciences
ISSN: 1449-2288
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ISSN: 1449-2288
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Int J Biol Sci 2010; 6(7):796-805. doi:10.7150/ijbs.6.796 This issue Cite
Review
Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Citation:
Chun YS, Chaudhari P, Jang YY. Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease. Int J Biol Sci 2010; 6(7):796-805. doi:10.7150/ijbs.6.796. https://www.ijbs.com/v06p0796.htm
Other stylesAbstract
The recent advances in the induced pluripotent stem cell (iPSC) research have significantly changed our perspectives on regenerative medicine by providing researchers with a unique tool to derive disease-specific stem cells for study. In this review, we describe the human iPSC generation from developmentally diverse origins (i.e. endoderm-, mesoderm-, and ectoderm- tissue derived human iPSCs) and multistage hepatic differentiation protocols, and discuss both basic and clinical applications of these cells including disease modeling, drug toxicity screening/drug discovery, gene therapy and cell replacement therapy.
Keywords: Stem Cell, Disease Modeling, Drug Screening, Liver Disease
Citation styles
APA
Chun, Y.S., Chaudhari, P., Jang, Y.Y. (2010). Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease. International Journal of Biological Sciences, 6(7), 796-805. https://doi.org/10.7150/ijbs.6.796.
ACS
Chun, Y.S.; Chaudhari, P.; Jang, Y.Y. Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease. Int. J. Biol. Sci. 2010, 6 (7), 796-805. DOI: 10.7150/ijbs.6.796.
NLM
Chun YS, Chaudhari P, Jang YY. Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease. Int J Biol Sci 2010; 6(7):796-805. doi:10.7150/ijbs.6.796. https://www.ijbs.com/v06p0796.htm
CSE
Chun YS, Chaudhari P, Jang YY. 2010. Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease. Int J Biol Sci. 6(7):796-805.
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