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Volume 20 (2); 2024

Research Papers

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Elevated SLC40A1 impairs cardiac function and exacerbates mitochondrial dysfunction, oxidative stress, and apoptosis in ischemic myocardia Renqian Feng, Di Wang, Tiantian Li, Xulin Liu, Tingwei Peng, Mingchuan Liu, Gaotong Ren, Haowei Xu, Haixia Luo, Denghui Lu, Bingchao Qi, Mingming Zhang, Yan Li Int. J. Biol. Sci. 2024; 20(2): 414-432. doi:10.7150/ijbs.89368 Full text PDF PubMed PMC


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METTL3 boosts mitochondrial fission and induces cardiac fibrosis after ischemia/reperfusion injury Li Ma, Xing Chang, Jing Gao, Ying Zhang, Ye Chen, Hao Zhou, Na Zhou, Na Du, Jiamin Li, Jiachen Bi, Ziyue Chen, Xinxin Chen, Qingyong He Int. J. Biol. Sci. 2024; 20(2): 433-445. doi:10.7150/ijbs.87535 Full text PDF PubMed PMC


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VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk Lu Wang, Lifen Zhang, Lin Zhao, Shan Shao, Qian Ning, Xin Jing, Yujiao Zhang, Fengyu Zhao, Xizhi Liu, Shanzhi Gu, Xinhan Zhao, Minna Luo Int. J. Biol. Sci. 2024; 20(2): 446-463. doi:10.7150/ijbs.86085 Full text PDF PubMed PMC


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ADAR1 protects pulmonary macrophages from sepsis-induced pyroptosis and lung injury through miR-21/A20 signaling Xiaojun Zhao, Jiangang Xie, Chujun Duan, Linxiao Wang, Yi Si, Shanshou Liu, Qianmei Wang, Dan Wu, Yifan Wang, Wen Yin, Ran Zhuang, Junjie Li Int. J. Biol. Sci. 2024; 20(2): 464-485. doi:10.7150/ijbs.86424 Full text PDF PubMed PMC


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Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer Min Wu, Jiuqing Xie, Yajing Xing, Lin Zhang, Huang Chen, Bin Tang, Miaoran Zhou, Shiyi Lv, Dongxia Huang, Shuyi Jian, Cili Zhou, Mingyao Liu, Weikai Guo, Yihua Chen, Zhengfang Yi Int. J. Biol. Sci. 2024; 20(2): 486-501. doi:10.7150/ijbs.86303 Full text PDF PubMed PMC


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p32 regulates glycometabolism and TCA cycle to inhibit ccRCC progression via copper-induced DLAT lipoylation oligomerization Shaoping Tian, Rui Wang, Yiting Wang, Ruibing Chen, Tianyu Lin, Xuesong Xiao, Xinyu Liu, Justin Eze Ideozu, Hua Geng, Yong Wang, Dan Yue Int. J. Biol. Sci. 2024; 20(2): 516-536. doi:10.7150/ijbs.84399 Full text PDF PubMed PMC


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Cisplatin-induced Pyroptosis Enhances the Efficacy of PD-L1 Inhibitor in Small-Cell Lung Cancer via GSDME/IL12/CD4Tem Axis Wendi Xuzhang, Tingting Lu, Weiqiu Jin, Yongfeng Yu, Ziming Li, Lan Shen, Xiaomin Niu, Xinghao Ai, Liliang Xia, Shun Lu Int. J. Biol. Sci. 2024; 20(2): 537-553. doi:10.7150/ijbs.89080 Full text PDF PubMed PMC


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Protein arginine methyltransferase 1 is required for the maintenance of adult small intestinal and colonic epithelial cell homeostasis Zhaoyi Peng, Lingyu Bao, Bingyin Shi, Yun-Bo Shi Int. J. Biol. Sci. 2024; 20(2): 554-568. doi:10.7150/ijbs.89958 Full text PDF PubMed PMC


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MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism Shanshan Liu, Shuai Han, Cuili Wang, Hongjun Chen, Qiannan Xu, Shi Feng, Yucheng Wang, Jihong Yao, Qin Zhou, Xuanli Tang, Li Lin, Lidan Hu, Alan J Davidson, Bing Yang, Cunqi Ye, Fan Yang, Jianhua Mao, Chao Tong, Jianghua Chen, Hong Jiang Int. J. Biol. Sci. 2024; 20(2): 569-584. doi:10.7150/ijbs.89291 Full text PDF PubMed PMC


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SIRT5-related lysine demalonylation of GSTP1 contributes to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy Can Wei, Meixin Shi, Shiyun Dong, Zhitao Li, Bingbing Zhao, Dan Liu, Guopeng Li, Jie Cen, Ligen Yu, Xiao Liang, Lili Shi Int. J. Biol. Sci. 2024; 20(2): 585-605. doi:10.7150/ijbs.83306 Full text PDF PubMed PMC


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TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production Eunhye Jung, Eun Bok Baek, Eun-Ju Hong, Jee Hyun Kang, Suyoung Park, Sehee Park, Eui-Ju Hong, Young-Eun Cho, Je-Won Ko, Young-Suk Won, Hyo-Jung Kwon Int. J. Biol. Sci. 2024; 20(2): 606-620. doi:10.7150/ijbs.90781 Full text PDF PubMed PMC


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ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma Xiaofei Wang, Lin Yao, Zheng Li, Jiaen Zhang, Mingjian Ruan, Yelin Mulati, Ying Gan, Qian Zhang Int. J. Biol. Sci. 2024; 20(2): 643-663. doi:10.7150/ijbs.89785 Full text PDF PubMed PMC


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Polysaccharide isolated from Grifola frondosa eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses Xiangmin Li, Qinzhao Ruan, Weining Yang, Huixiang Tian, Nan Wu, Javeria Qadir, Juan Wang, Huiping Hu, Yuanchao Liu, Manjun Cai, Burton B. Yang, Yizhen Xie, Qingping Wu Int. J. Biol. Sci. 2024; 20(2): 664-679. doi:10.7150/ijbs.85276 Full text PDF PubMed PMC


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Irisin attenuates vascular remodeling in hypertensive mice induced by Ang II by suppressing Ca2+-dependent endoplasmic reticulum stress in VSMCs Ru-li Li, Cai-li Zhuo, Xin Yan, He Li, Lan Lin, Ling-yu Li, Qiying Jiang, Die Zhang, Xue-mei Wang, Lin-ling Liu, Wen-jing Huang, Ying-ling Wang, Xin-yue Li, Yan Mao, Yixin Chen, Xiao Liu, Quan-chen Xu, Yu-yan Cai, Xi-jing Yang, Hong-ying Chen, Si-si Wu, Wei Jiang Int. J. Biol. Sci. 2024; 20(2): 680-700. doi:10.7150/ijbs.84153 Full text PDF PubMed PMC


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Selective Autophagy Receptor NBR1 Retards Nucleus Pulposus Cell Senescence by Directing the Clearance of SRBD1 Honghai Song, Yutao Zhu, Chuan Hu, Qianyu Liu, Yang Jin, Pan Tang, Jiechao Xia, Dingqi Xie, Sicheng Jiang, Geliang Yao, Zhili Liu, Zhijun Hu Int. J. Biol. Sci. 2024; 20(2): 701-717. doi:10.7150/ijbs.90186 Full text PDF PubMed PMC


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LncRNA CRNDE Drives the Progression of Hepatocellular Carcinoma by inducing the Immunosuppressive Niche Xianying Li, Shuhang Liang, Mingming Fei, Kun Ma, Linmao Sun, Yao Liu, Lianxin Liu, Jiabei Wang Int. J. Biol. Sci. 2024; 20(2): 718-732. doi:10.7150/ijbs.85471 Full text PDF PubMed PMC


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Pyroptotic Macrophage-Derived Microvesicles Accelerate Formation of Neutrophil Extracellular Traps via GSDMD-N-expressing Mitochondrial Transfer during Sepsis Liangjian Kuang, Yongjian Wu, Jingxian Shu, Jingwen Yang, Haibo Zhou, Xi Huang Int. J. Biol. Sci. 2024; 20(2): 733-750. doi:10.7150/ijbs.87646 Full text PDF PubMed PMC


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Inhibition of the HMGB1/RAGE axis protects against cisplatin-induced ototoxicity via suppression of inflammation and oxidative stress Xiangyun Qiao, Wen Li, Zhiwei Zheng, Chang Liu, Liping Zhao, Yingzi He, Huawei Li Int. J. Biol. Sci. 2024; 20(2): 784-800. doi:10.7150/ijbs.82003 Full text PDF PubMed PMC


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Connexin 36 Mediated Intercellular Endoplasmic Reticulum Stress Transmission Induces SSTA Resistance in Growth Hormone Pituitary Adenoma Zihan Wang, Zhuowei Lei, Quanji Wang, Qian Jiang, Zhuo Zhang, Xiaojin Liu, Biao Xing, Sihan Li, Xiang Guo, Yanchao Liu, Xingbo Li, Yiwei Qi, Kai Shu, Huaqiu Zhang, Yimin Huang, Ting Lei Int. J. Biol. Sci. 2024; 20(2): 801-817. doi:10.7150/ijbs.86736 Full text PDF PubMed PMC

Reviews

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Towards improving the prognosis of stroke through targeting the circadian clock system Suliman Khan, Rabeea Siddique, Yang Liu, V. Wee Yong, Mengzhou Xue Int. J. Biol. Sci. 2024; 20(2): 403-413. doi:10.7150/ijbs.88370 Full text PDF PubMed PMC


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Uncovering the flip side of immune checkpoint inhibitors: a comprehensive review of immune-related adverse events and predictive biomarkers Yan-Dong Miao, Wu-Xia Quan, Xiao-Long Tang, Wei-Wei Shi, Qing Li, Rui Jian Li, Jiang-Tao Wang, Jian Gan, Xin Dong, Liang Hao, Wen-Yu Luan, Fang Zhang Int. J. Biol. Sci. 2024; 20(2): 621-642. doi:10.7150/ijbs.89376 Full text PDF PubMed PMC


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Molecular Modulators and Receptors of Selective Autophagy: Disease Implication and Identification Strategies Ming-Yue Wu, Zhe-Wei Li, Jia-Hong Lu Int. J. Biol. Sci. 2024; 20(2): 751-764. doi:10.7150/ijbs.83205 Full text PDF PubMed PMC


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Radiotherapy in Preclinical Models of Brain Metastases: A Review and Recommendations for Future Studies Wen Shi, Guilong Tanzhu, Liu Chen, Jiaoyang Ning, Hongji Wang, Gang Xiao, Haiqin Peng, Di Jing, Huadong Liang, Jing Nie, Min Yi, Rongrong Zhou Int. J. Biol. Sci. 2024; 20(2): 765-783. doi:10.7150/ijbs.91295 Full text PDF PubMed PMC

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