Int J Biol Sci
2006; 2(2):87-92.
doi:10.7150/ijbs.2.87 This issueCite
Research Paper
Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study
Juan Pascual-Anaya, Salvatore D'Aniello
Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain
Citation:
Pascual-Anaya J, D'Aniello S. Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. Int J Biol Sci 2006; 2(2):87-92. doi:10.7150/ijbs.2.87. https://www.ijbs.com/v02p0087.htm
The cephalochordate amphioxus is the closest invertebrate relative to vertebrates. In this study, using HPLC technique, free L-amino acids (L-AAs) and D-aspartic acid (D-Asp) have been detected in the nervous system of the amphioxus Branchiostoma lanceolatum. Among other amino acids glutamate, aspartate, glycine, alanine and serine are the amino acids found at the greatest concentrations. As it occurs in the nervous system of other animal phyla, glutamate (L-Glu) and aspartate (L-Asp) are present at very high concentrations in the amphioxus nervous system compared to other amino acids, whereas the concentration of taurine and γ-aminobutyric acid (GABA) is very low. Interestingly, as it is the case in vertebrates, D-aspartic acid is present as an endogenous compound in amphioxus nervous tissues. The physiological function of excitatory amino acids, and D-aspartate in particular, are discussed in terms of evolution of the nervous system under an Evo-fun (Evolution of function) perspective.
Pascual-Anaya, J., D'Aniello, S. (2006). Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. International Journal of Biological Sciences, 2(2), 87-92. https://doi.org/10.7150/ijbs.2.87.
ACS
Pascual-Anaya, J.; D'Aniello, S. Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. Int. J. Biol. Sci. 2006, 2 (2), 87-92. DOI: 10.7150/ijbs.2.87.
NLM
Pascual-Anaya J, D'Aniello S. Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. Int J Biol Sci 2006; 2(2):87-92. doi:10.7150/ijbs.2.87. https://www.ijbs.com/v02p0087.htm
CSE
Pascual-Anaya J, D'Aniello S. 2006. Free amino acids in the nervous system of the amphioxus Branchiostoma lanceolatum. A comparative study. Int J Biol Sci. 2(2):87-92.