◂ Last issue Archive   

Volume 22 (12); 2026

Research Papers

Graphic abstract

Intestine-specific Faf2 depletion ameliorates obesity and metabolic dysfunction-associated steatotic liver disease by impairing lipid absorption Jingjing Zhang, Norihiro Imai, Jinglei Cheng, Akiko Sugiyama, Hanna Kawecka, Dongming Liu, Michitaka Suzuki, Yuki Ohsaki, Shinya Yokoyama, Kenta Yamamoto, Takanori Ito, Keiko Maeda, Yoji Ishizu, Takashi Honda, Tetsuya Ishikawa, Michał Woźniak, Hiroaki Wake, David E. Cohen, Hiroki Kawashima Int. J. Biol. Sci. 2026; 22(12): 6261-6280. doi:10.7150/ijbs.134379 Full text PDF


Graphic abstract

Targeting Netrin-1 Mediates the Suppression of Osteolytic Bone Metastasis in Breast Cancer by Ugonin L Trung-Loc Ho, Wei-Cheng Chen, Chun-Lin Liu, Kuan-Ying Lai, Chih-Chuang Liaw, Lan-Yun Chang, Chih-Hao Lu, Hsiao-Chi Tsai, Yi-Chin Fong, Jeng-Hung Guo, Tzu-Min Huang, Chih-Ying Wu, Chih-Hsin Tang Int. J. Biol. Sci. 2026; 22(12): 6298-6315. doi:10.7150/ijbs.128973 Full text PDF


Graphic abstract

ALYREF-mediated m5C modification of CCNA1 drives escape from cell-cycle arrest and contributes to pazopanib resistance in Renal Cell Carcinoma Zeyi Lu, Yang Li, Ziwei Zhu, Fan Li, Yiming Ding, Lifeng Ding, Ruyue Wang, Yudong Lin, Wenqin Luo, Xudong Mao, Haohua Lu, Yejinpeng Wang, Mengxuan Li, Yuanlei Chen, Zhehao Xu, Yi Lu, Qiming Zheng, Haiyun Xie, Zhenwei Zhou, Liqun Xia, Gonghui Li, Mingchao Wang Int. J. Biol. Sci. 2026; 22(12): 6319-6337. doi:10.7150/ijbs.131368 Full text PDF


Graphic abstract

Glycosylation of B7-H3 Promotes CD8+ T Cell Exhaustion by Inhibiting the Endosome-Lysosome Pathway in HCC Yifan Yu, Jiaxing Liu, Zhixiong Hao, Yu Li, Guangpeng He, Xuzhe Wang, Liang Yang, Xiaodan Liu, Hangyu Li, Xueqiang Peng Int. J. Biol. Sci. 2026; 22(12): 6338-6362. doi:10.7150/ijbs.126547 Full text PDF


Graphic abstract

Oridonin targets PRDX1 to promote apoptosis by inducing ROS-mediated ER stress and modulating autophagy Ziyang Ding, Sisi Wang, Junhui Chen, Yali Song, Zhou Zhu, Haibo Tong, Ashok Iyaswamy, Peng Chen, Xu Wei, Wei Zhang, Jigang Wang, Chuanbin Yang, Yulin Feng Int. J. Biol. Sci. 2026; 22(12): 6363-6380. doi:10.7150/ijbs.110208 Full text PDF


Graphic abstract

Targeting Kupffer Cell CD44-Mediated Ammonia Death via the ELAVL1-GLS Metabolic Circuit in Radiation-Induced Liver Disease Yanyan Lin, Shuxuan Wang, Bufu Tang, Pan Zhou, Xiaojun Zhang, Huanliang Chen, Jiaoyang Yang, Shisuo Du, Qian-Qian Zhao, Zhao-Chong Zeng Int. J. Biol. Sci. 2026; 22(12): 6417-6433. doi:10.7150/ijbs.136823 Full text PDF


Graphic abstract

Mechanical stress-induced STAT3/YAP signaling in fibroblasts programs immunosuppressive lymph node remodeling in lung squamous carcinoma Jie Cai, Zhao An, Wei Gao, Ryan Li, Zhe-Sheng Chen, An Li, Lei Zhu, Yingran Shen Int. J. Biol. Sci. 2026; 22(12): 6434-6447. doi:10.7150/ijbs.132656 Full text PDF

Reviews

Graphic abstract

Complex Roles of Insect Cytochrome P450s in Chemical Adaptation Qi-Ren Chen, Timothy W. Moural, Fang Zhu Int. J. Biol. Sci. 2026; 22(12): 6281-6297. doi:10.7150/ijbs.135523 Full text PDF


Graphic abstract

Exploring Lipid Metabolic Reprogramming: Mechanistic Insights and Implications for Tumor Radiotherapy Ruiqiu Zhu, Ying Wan, Jinrong Wei, Limin Jin, Yuntian Shen, Yaqun Zhu, Qiliang Peng Int. J. Biol. Sci. 2026; 22(12): 6381-6416. doi:10.7150/ijbs.133227 Full text PDF

Commentary

Graphic abstract

Immune Imprinting and Antigenic Drift as Determinants of SARS-CoV-2 Vaccine Performance Seung-Jae Lee, Jaehoon Bae, Sang Hoon Lee Int. J. Biol. Sci. 2026; 22(12): 6316-6318. doi:10.7150/ijbs.130233 Full text PDF

Popup Image