Long Noncoding RNA: Recent Updates in Atherosclerosis

Li, Hao; Zhu, Hongming; Ge, Junbo

doi:10.7150/ijbs.14430

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Int J Biol Sci 2016; 12(7):898-910. doi:10.7150/ijbs.14430 This issue Cite

Research Paper

Long Noncoding RNA: Recent Updates in Atherosclerosis

Hao Li¹, Hongming Zhu^2✉, Junbo Ge^1,3✉

1. Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
2. Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
3. Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Citation:

Li H, Zhu H, Ge J. Long Noncoding RNA: Recent Updates in Atherosclerosis. Int J Biol Sci 2016; 12(7):898-910. doi:10.7150/ijbs.14430. https://www.ijbs.com/v12p0898.htm

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Abstract

Long noncoding RNAs belong to a class of noncoding RNAs longer than 200 nucleotides with the epigenetic regulation potential. As a novel molecular regulator, lncRNAs are often dysregulated in various pathological conditions and display multiple functions in a wide range of biological processes. Given that recent studies have indicated that lncRNAs are involved in atherosclerosis-related smooth muscle cell, endothelial cell, macrophage and lipid metabolism regulation, it is pertinent to understand the potential function of lncRNAs in atherosclerosis development. This review will highlight the recent updates of lncRNAs in atherogenesis and also discuss their potential roles as novel therapeutic targets.

Keywords: Long noncoding RNA, Atherosclerosis, Gene regulation

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APA

Li, H., Zhu, H., Ge, J. (2016). Long Noncoding RNA: Recent Updates in Atherosclerosis. International Journal of Biological Sciences, 12(7), 898-910. https://doi.org/10.7150/ijbs.14430.

ACS

Li, H.; Zhu, H.; Ge, J. Long Noncoding RNA: Recent Updates in Atherosclerosis. Int. J. Biol. Sci. 2016, 12 (7), 898-910. DOI: 10.7150/ijbs.14430.

NLM

Li H, Zhu H, Ge J. Long Noncoding RNA: Recent Updates in Atherosclerosis. Int J Biol Sci 2016; 12(7):898-910. doi:10.7150/ijbs.14430. https://www.ijbs.com/v12p0898.htm

CSE

Li H, Zhu H, Ge J. 2016. Long Noncoding RNA: Recent Updates in Atherosclerosis. Int J Biol Sci. 12(7):898-910.

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