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Review Metabolic Barriers to Cancer Immunotherapy: Multiscale Mechanisms from Organelle Dysfunction to Organ-Specific Constraints Zichen Gui, Xiaoyin Yuan, Xiaoping Chen, Qibo Huang, Bixiang Zhang, Junnan Liang Int. J. Biol. Sci. 2026; 22(15): 8408-8447. doi:10.7150/ijbs.137618 Full text PDF


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Review Extracellular Mitochondrial Components as Emerging Biomarkers and Therapeutic Targets in Human Diseases Kuan-Hao Tsui, Emmanuel Naveen Raj, Andy P. Tsai, Boyang Wang, Chen-Yueh Wen, Chia-Jung Li Int. J. Biol. Sci. 2026; 22(15): 8390-8407. doi:10.7150/ijbs.140360 Full text PDF


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Research Paper Young plasma-derived exosomes deliver YOD1 to induce M2 polarization and ameliorate osteoporosis via mTOR signaling pathways Jiahao Wang, Xiaokang Zhang, Siteng Li, Qi Zhang, Jiheng Xiao, Chengbin Huang, Jianpeng Chen, Yang Luo, Zeming Shan, Ziping Chen, Ling Wang, Yingze Zhang Int. J. Biol. Sci. 2026; 22(15): 8364-8389. doi:10.7150/ijbs.138620 Full text PDF


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Research Paper RAB7A-enriched extracellular vesicles drive early-metastasis and immune evasion in triple-negative breast cancer Hanyi Zhong, Han Wang, Weiqi Gao, Ziling Zhou, Shoutang Wang, Ou Huang, Renhong Huang, Zheng Wang, Kunwei Shen Int. J. Biol. Sci. 2026; 22(15): 8348-8363. doi:10.7150/ijbs.138205 Full text PDF


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Research Paper OLFM4 promotes intrahepatic cholangiocarcinoma progression through a PKM2-glycolysis-histone lactylation feedback loop Shuochen Liu, Kai Cao, Changan Chen, Xiao Xu, Jijun Shan, Chang Li, Ruixiang Chen, Yananlan Chen, Jiang Chang, Wangjie Jiang, Yaodong Zhang, Dong Wang, Changxian Li, Xiangcheng Li Int. J. Biol. Sci. 2026; 22(15): 8333-8347. doi:10.7150/ijbs.135505 Full text PDF


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Review Cross-cutting circuits in heart failure with preserved ejection fraction: Integrating adipokine biology, mechanotransduction, and precision targeting KaiJian Zhang, Hui Li, Wei Wen, BuChun Zhang Int. J. Biol. Sci. 2026; 22(15): 8318-8332. doi:10.7150/ijbs.137328 Full text PDF

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Issue 13; 2026

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Editor-in-Chief: Chuxia Deng, PhD, Chair Professor, College of Synthetic Biology, Shenzhen University of Advanced Technology

Editor-in-Chief's Profile



Plagiarism Policy (please read before submission): This journal maintains a zero-tolerance policy towards plagiarism. Manuscripts are screened for plagiarism before and after publication. If a published paper is found to contain plagiarism, it will be retracted and the authors' institutions and department heads will be notified to take appropriate action. This policy also applies to data fabrication and image manipulation.



Journal of Genomics articles:

Research Paper Draft Genome Sequence of Multidrug-Resistant Acinetobacter baumannii smu isolated from a Bloodstream Infection in Sikkim, India Rekha Sharma, Rohit Das, Yezey Rikzing Bhutia, Neha Pradhan, Anil Bhattarai J. Genomics 2026; 14: 18-29. Full text PDF PubMed PMC

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