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Volume 20 (13); 2024

Research Papers

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Single-Cell RNA-Sequencing Identifies Bone Marrow-Derived Progenitor Cells as a Main Source of Extracellular Matrix-Producing Cells Across Multiple Organ-Based Fibrotic Diseases
Yu Zhong, Biao Wei, Wenbiao Wang, Junzhe Chen, Wenjing Wu, Liying Liang, Xiao-Ru Huang, Cheuk-Chun Szeto, Xueqing Yu, David J. Nikolic-Paterson, Hui-Yao Lan
Int. J. Biol. Sci. 2024; 20(13): 5027-5042. doi:10.7150/ijbs.98839
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AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment—Efficacy and Mechanism
Tao Dong, Leonard Barasa, Xin Yu, Wenlu Ouyang, Liujiazi Shao, Chao Quan, Su He Wang, Jifeng Zhang, Morgan Salmon, Allan Tsung, Hasan B. Alam, Jianjie Ma, Paul R. Thompson, Yongqing Li
Int. J. Biol. Sci. 2024; 20(13): 5043-5055. doi:10.7150/ijbs.97166
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Chimerization of human ESC-derived extraembryonic cells with the mouse blastocyst
Siyi Fu, Borong Huang, Enqin Li, Xiaoling Xu, Ren-He Xu
Int. J. Biol. Sci. 2024; 20(13): 5056-5069. doi:10.7150/ijbs.99519
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PRDX1 inhibits ferroptosis by binding to Cullin-3 as a molecular chaperone in colorectal cancer
Yujia Song, Xiaohui Wang, Yuqi Sun, Nianhua Yu, Yajie Tian, Jinli Han, Xianjun Qu, Xinfeng Yu
Int. J. Biol. Sci. 2024; 20(13): 5070-5086. doi:10.7150/ijbs.99804
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HNF4A-AS1 inhibits the progression of hepatocellular carcinoma by promoting the ubiquitin-modulated degradation of PCBP2 and suppressing the stability of ARG2 mRNA
Wenbo Jia, Liang Yu, Bin Xu, Yanzhi Feng, Jinyi Wang, Deming Zhu, Chao Xu, Litao Liang, Yongping Zhou, Lianbao Kong, Wenzhou Ding
Int. J. Biol. Sci. 2024; 20(13): 5087-5108. doi:10.7150/ijbs.95276
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KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300
Wendan Yu, Shilong Han, Sheng Hu, Liyuan Ru, Chunyu Hua, Guoqing Xue, Guohui Zhang, Kuan Lv, Hanxiao Ge, Meiyi Wang, Lina Zheng, Jie Zhou, Shuai Hou, Yun Teng, Wuguo Deng, Wei Guo
Int. J. Biol. Sci. 2024; 20(13): 5127-5144. doi:10.7150/ijbs.98668
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Exploring the Mechanism of Ferroptosis Induction by Sappanone A in Cancer: Insights into the Mitochondrial Dysfunction Mediated by NRF2/xCT/GPX4 Axis
Junyan Wang, Haowen Zhuang, Xiaocui Yang, Zhijiang Guo, Kainan Zhou, Nanyang Liu, Yang An, Ye Chen, Zhongzheng Zhang, Mengyuan Wang, Jinhong Chen, Chun Li, Xing Chang
Int. J. Biol. Sci. 2024; 20(13): 5145-5161. doi:10.7150/ijbs.96748
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HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling
Yiming Zhang, Ruilin Pan, Kun Li, Lek Hang Cheang, Jing Zhao, Zhangfeng Zhong, Shaoping Li, Jinghao Wang, Xiaofang Zhang, Yanmei Cheng, Xiaofei Zheng, Rongrong He, Huajun Wang
Int. J. Biol. Sci. 2024; 20(13): 5162-5190. doi:10.7150/ijbs.100015
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Integrated analysis of tumor and adjacent non-tumor proteomic data reveals SERPINH1 as a recurrence biomarker and drug target in hepatocellular carcinoma
Yushan Hou, Yiming Zhang, Kun Zheng, Han Wang, Yingying Zhou, Yuanjun Zhai, Fuchu He, Chunyan Tian, Aihua Sun
Int. J. Biol. Sci. 2024; 20(13): 5191-5207. doi:10.7150/ijbs.99734
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USP44 inactivation accelerates the progression of thyroid cancer by inducing ubiquitylation and degradation of p21
Yan Liu, Mengmeng Yuan, Xinxin Xu, Huini Yang, Yao Yao, Peng Hou, Wei Yu, Meiju Ji
Int. J. Biol. Sci. 2024; 20(13): 5223-5238. doi:10.7150/ijbs.99817
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Amlexanox Enforces Osteogenic Differentiation and Bone Homeostasis Through Inhibiting Ubiquitin-Dependent Degradation of β-Catenin
Qian He, Zhouboran Liu, Xuan Xia, Jun Zeng, Yuling Liu, Jingqiong Xun, Meilu Liu, Yueming Mei, Ruchun Dai
Int. J. Biol. Sci. 2024; 20(13): 5254-5271. doi:10.7150/ijbs.101507
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Identification of miR-6794-3p as a suppressor in pancreatic cancer metastasis
Ha Gyeong Kim, Yunmi Cho, Jae-Seon Lee, Eun-Taex Oh, Heon Joo Park
Int. J. Biol. Sci. 2024; 20(13): 5272-5292. doi:10.7150/ijbs.98490
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Theophylline derivatives promote primordial follicle activation via cAMP-PI3K/Akt pathway and ameliorate fertility deficits in naturally aged mice
Wenbo Zhang, Longwei Gao, Xiaodan Zhang, Yashuang Weng, Yan Du, Yan-Li Sun, Hongwei Wei, Tiantian Hao, Yuezhou Chen, Xiaoyan Liang, Meijia Zhang
Int. J. Biol. Sci. 2024; 20(13): 5312-5329. doi:10.7150/ijbs.99936
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USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway
Jie Wang, Lang Gan, Fenghao Liu, Qin Yang, Qingsong Deng, Di Jiang, Chengcheng Zhang, LeiDa Zhang, XiaoJun Wang
Int. J. Biol. Sci. 2024; 20(13): 5343-5362. doi:10.7150/ijbs.92278
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Leveraging Patient-Derived Organoids for Personalized Liver Cancer Treatment
Jianhua Rao, Chao Song, Yangyang Hao, Zaozao Chen, Sidu Feng, Shihui Xu, Xiaoyue Wu, Zhengfeng Xuan, Ye Fan, Wenzhu Li, Junda Li, Yong Ren, Jian Li, Feng Cheng, Zhongze Gu
Int. J. Biol. Sci. 2024; 20(13): 5363-5374. doi:10.7150/ijbs.96317
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NUSAP1 is Upregulated by Estrogen to Promote Lung Adenocarcinoma Growth and Serves as a Therapeutic Target
Shaoping Zhang, Xiaozhen Zhang, Wenjian Huang, Ganling Jiang, Yuanxin Mo, Liuxia Wei, Pingming Fan, Maojian Chen, Wei Jiang
Int. J. Biol. Sci. 2024; 20(13): 5375-5395. doi:10.7150/ijbs.100188
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Reviews

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A new perspective on the therapeutic potential of tumor metastasis: targeting the metabolic interactions between TAMs and tumor cells
Xuan Zhao, Tong Ren, Sijin Li, Xu Wang, Rui Hou, Zhangchun Guan, Dan Liu, Junnian Zheng, Ming Shi
Int. J. Biol. Sci. 2024; 20(13): 5109-5126. doi:10.7150/ijbs.99680
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Deubiquitinases in Ovarian Cancer: Role in Drug Resistance and Tumor Aggressiveness
Giovanni Luca Beretta, Matteo Costantino, Luca Mirra, Pietro Pettinari, Paola Perego
Int. J. Biol. Sci. 2024; 20(13): 5208-5222. doi:10.7150/ijbs.100355
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Unveiling the Role of Mechanical Microenvironment in Hepatocellular Carcinoma: Molecular Mechanisms and Implications for Therapeutic Strategies
Jiachen Hong, Jiongjie Yu, Damiano Buratto, Wei Chen, Ruhong Zhou, Sunbin Ling, Xiao Xu
Int. J. Biol. Sci. 2024; 20(13): 5239-5253. doi:10.7150/ijbs.102706
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Three-Dimensional In Vitro Cell Cultures as a Feasible and Promising Alternative to Two-Dimensional and Animal Models in Cancer Research
Andrea Esposito, Alessandra Ferraresi, Letizia Vallino, Beatrice Garavaglia, Danny N. Dhanasekaran, Ciro Isidoro
Int. J. Biol. Sci. 2024; 20(13): 5293-5311. doi:10.7150/ijbs.96469
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Molecular changes in intraocular fluid: implications for myopia
Zewei Zhang, Lingfeng Lv, Dongmei Chen, Fang Li, Jibo Zhou
Int. J. Biol. Sci. 2024; 20(13): 5330-5342. doi:10.7150/ijbs.101438
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