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Volume 22 (6); 2026

Research Papers

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IGF2BP2 Deficiency in Macrophages Impairs Migration, Reprograms Metabolism, and Limits Tumor Progression
Hanna S. Schymik, Selina Wrublewsky, Marcus Höring, Gerhard Liebisch, Simon Both, Gilles Gasparoni, Caroline Bickelmann, Hanah Robertson, Charlotte Dahlem, Jörn Walter, Volkhard Helms, Matthias W. Laschke, Emmanuel Ampofo, Jessica Hoppstädter, Alexandra K. Kiemer
Int. J. Biol. Sci. 2026; 22(6): 2754-2773. doi:10.7150/ijbs.122142
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Targeting STARD10 Alleviates Steatotic Liver Injury by Suppressing YBX1/ACSL1-Mediated Ferroptosis
Zhipeng Yang, Wenjie Zhang, Wenjie Gao, Junbo Song, Hongmin Kuang, Xin Hong, Liqiang Zhao, Chuheng Gou, Zhibin Lin, Quancheng Wang, Xuan Zhang, Kefeng Dou
Int. J. Biol. Sci. 2026; 22(6): 2786-2805. doi:10.7150/ijbs.127662
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Piezo1-Fstl1 Axis in Fracture Healing: Modulation of the Chondrocyte Inflammation-ROS-Mitochondrial Damage Cascade and Application of Smart Delivery System
Tao Zhang, Haoran Wang, Guangzhao Hou, Siming Jia, Kai Ding, Qian Xiao, Jinbo Liu, Yajiang Dai, Gang Lv, Zhiyong Hou, Yingze Zhang, Juan Wang, Hongzhi Lv, Wei Chen
Int. J. Biol. Sci. 2026; 22(6): 2806-2826. doi:10.7150/ijbs.125814
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Identification of a Novel PDRG1-EZH2-p21 Pathway Controlling Senescence and Tumor Progression in Hepatocellular Carcinoma
Qiang Yang, Lilong Zhang, Wei Li, Zhengle Zhang, Jing Tao, Yuping Rong, Weixing Wang
Int. J. Biol. Sci. 2026; 22(6): 2827-2841. doi:10.7150/ijbs.129113
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Clonotype-Resolved Single-Cell Multi-Omics Unlocks the Profile of Tumor-Infiltrating CD39⁺CD8⁺ T Cells and Enables Adoptive Cell Therapy for Solid Tumor
Zihan Zhao, Xiangyu Wu, Qingyang Jin, Xin Yang, Wenjie Zhu, Ning Jiang, Tianyao Liu, Tianhang Li, Feng Fang, Hongqian Guo, Rong Yang
Int. J. Biol. Sci. 2026; 22(6): 2869-2884. doi:10.7150/ijbs.130389
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Synergistic Neurotoxicity of environmental Cadmium and Paraquat in Parkinsonism: Unveiling the Mito-ROS/OPA1/Caspase-3/GSDME-driven Apoptosis Axis
Yufei Luo, Yingying Lu, Yancheng Tang, Xuejun Zhao, Junpu Wang, Yifan Liu, Sijia Jiang, Yuyuan Zhu, Jiaqi Qi, Linlin Xing, Chenghao Yan, Xu Liu, Cainian Huang, Haiji Wang, Haodong Xu, Liming Wang
Int. J. Biol. Sci. 2026; 22(6): 2885-2905. doi:10.7150/ijbs.126979
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Investigating the Mechanistic Link Between Lactate-Induced Histone Lactylation and Cellular Senescence in Osteoarthritis Chondrocytes: Implications for Therapy
Rongtai Zuo, Chenliang Wu, Zhiqi Lin, Lingchi Kong, Feng Wang, Xuancheng Zhang, Jianxing Wei, Yi Lin, Erpeng Yang, Qinglin Kang, Shichang Zhao, Junjie Guan, Jinzhong Zhao
Int. J. Biol. Sci. 2026; 22(6): 2925-2949. doi:10.7150/ijbs.126483
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In vivo CRISPR/Cas9 Screening Reveals that UBE2L3 Modulates Autophagic Flux through TSC2 Ubiquitination and Potentiates PD-1 Blockade in Triple-Negative Breast Cancer
Jian Xu, Ling Cheng, Sien Ma, Chen Gan, Jiaying Chai, Xinyi Zheng, Longyu Hu, Meiwen Ling, Mingjun Zhang, Bao Zhao, Huaidong Cheng
Int. J. Biol. Sci. 2026; 22(6): 2950-2969. doi:10.7150/ijbs.124937
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Reviews

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Pancreatic cancer-associated myofibroblasts: a review
Marcin Banacki, Iwona Inkielewicz-Stepniak
Int. J. Biol. Sci. 2026; 22(6): 2774-2785. doi:10.7150/ijbs.121234
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Role of Copper Homeostasis and Cuproptosis in Cardiovascular Disease: Molecular Insights and Metabolic Perspectives
Xianzhe Yu, Dou Yuan, Yabo Wang, Leibo Wang, Lingling Zhu, Qi An, Yunfei Ling
Int. J. Biol. Sci. 2026; 22(6): 2842-2868. doi:10.7150/ijbs.126580
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Orchestrating Tumor Metastasis: Exosomes as Master Regulators of the Local and Distant Microenvironment
Yuanke Zhao, Aiyu Liu, Xi Zhang, Anqi Zeng, Linjiang Song
Int. J. Biol. Sci. 2026; 22(6): 2906-2924. doi:10.7150/ijbs.128203
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